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KMID : 0978920170180010048
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Korean Journal of Clinical Geriatrics
2017 Volume.18 No. 1 p.48 ~ p.51
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Alcoholic Wernicke Encephalopathy Presenting with Ataxic Gait and Diplopia
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Ko Ki-Dong
Lee Yoon-Taek
Lee Hyun
Hwang Hee-Young
Kim Kyoung-Kon
Suh Heuy-Sun
Hwang In-Cheol
Lee Kyu-Rae
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Abstract
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Wernicke’s encephalopathy is an acute, reversible neurologic disorder which arises as metabolic complication of thiamine (vitamin B1) deficiency, frequently associated with alcohol misuse. Although Wernicke’s encephalopathy is characterized by a classic triad of mental status changes, ataxia, and ocular motor abnormalities, heterogenous clinical manifestations are more common. Prompt and accurate diagnosis by clinical suspicion is important to avoid death or progression to Korsakoff syndrome with irreversible brain damage. Immediate supplementation of thiamine is the cornerstone of treatment despite no accepted consensus on the optimal regimen. In this case report, we describe a case of Wernicke’s encephalopathy, which presentd with typical symtoms in a 63-year-old man with chronic alcoholism and review related literature.
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KEYWORD
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Wernicke encephalopathy, Alcohol-Related disorders, Thiamine deficiency
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